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The purpose of the Pooled Cohort Equations is to estimate the risk of ASCVD within a 10-year period among patients who have never had one of these events in the past. Want to nerd out? Check out our interactive ASCVD visualization graphing toolĪSCVD stands for atherosclerotic cardiovascular disease, defined as a nonfatal myocardial infarction (heart attack), coronary heart disease death, or stroke. Individuals without clinical ASCVD or diabetes who are 40 to 75 years of age with LDL 70 to 189 mg/dL and a 10-year ASCVD risk of 7.5% or higherĪs shown above, among patients who do not otherwise have a compelling indication for statin therapy, the Pooled Cohort Equations can be used to estimate primary cardiovascular risk and potential benefit from statin therapy.Individuals 40 to 75 years of age with diabetes and an LDL 70 to 189 mg/dL without clinical ASCVD.Individuals with primary elevations of LDL ≥ 190 mg/dL.3Ĭurrent guidelines for the treatment of cholesterol to reduce cardiovascular risk recommend that the following four groups of patients will benefit from moderate- or high-intensity statin therapy: 2 In many ways, the Pooled Cohort Equations have been proposed to replace the Framingham Risk 10-year CVD calculation, which was recommended for use in the NCEP ATP III guidelines for high blood cholesterol in adults. 1 Patients are considered to be at "elevated" risk if the Pooled Cohort Equations predicted risk is ≥ 7.5%. This peer-reviewed online calculator uses the Pooled Cohort Equations to estimate the 10-year primary risk of ASCVD (atherosclerotic cardiovascular disease) among patients without pre-existing cardiovascular disease who are between 40 and 79 years of age.